It is best known for its roles in female reproduction: it is released in large amounts after distension of the cervix and vagina during labor, and after stimulation of the nipples, facilitating birth and breastfeeding, respectively. Recent studies have begun to investigate oxytocin's role in various behaviors, including social recognition, bonding, anxiety, trust, and maternal behaviors.
In a preliminary study, the hormone oxytocin was shown to be associated with the ability to maintain healthy interpersonal relationships and healthy psychological boundaries with other people. The study appears in the July issue of Psychiatry.
"This is one of the first looks into the biological basis for human attachment and bonding," said Rebecca Turner, PhD, UCSF adjunct assistant professor of psychiatry and lead author of the study. "Our study indicates that oxytocin may be mediating emotional experiences in close relationships."
The study builds upon previous knowledge of the important role oxytocin plays in the reproductive life of mammals. The hormone facilitates nest building and pup retrieval in rats, acceptance of offspring in sheep, and the formation of adult pair-bonds in prairie voles. In humans, oxytocin stimulates milk ejection during lactation, uterine contraction during birth, and is released during sexual orgasm in both men and women.
Turner and her colleagues tested the idea that oxytocin is released in response to intense emotional states in addition to physical cues. Twenty-six non-lactating women between the ages of 23 and 35 were asked to recall and re-experience a past relationship event that caused them to feel a positive emotion, such as love or infatuation, and a negative emotion, such as loss or abandonment. Because massage done on rats had previously been shown to influence oxytocin levels, the participants also received a 15-minute Swedish massage of the neck and shoulders. Blood samples were taken before, during, and after each of the three events to measure baseline oxytocin levels in the bloodstream and any change.
The results, on average, were of borderline significance - relaxation massage caused oxytocin levels to rise slightly and recollection of a negative emotion caused oxytocin levels to fall slightly. Recollection of a positive emotion, on average, had no effect.
What surprised the researchers, however, was how differently each woman responded. Some participants showed substantial increases and decreases while others were largely unaffected.
good work.
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(milktate?)